I am a highly motivated pharmacologist with solid history of driving research initiatives and delivering impactful scientific work. I am focused on team collaborations and possess adaptability in dynamic research environments. My expertise extends in in vitro, ex vivo, and in vivo drug development research for the treatment of cancer. I have conducted and analyzed over 40 in vivo tumour xenograft models and designed/executed multiple pharmacokinetic studies in rodents. I am a proven expertise in western blotting, cell culture, and flow cytometry and utilizing these techniques to elucidate drug mechanisms and optimize treatment strategies. I possess a strong track record in PK-PD correlation studies and thrive in collaborative environments. I am passionate about drug discovery and development, cancer cell biology, and in vivo efficacy studies, with a focus on combination therapies for cancer treatment. My work has led to the identification of two promising drug candidates; one is a first in class CDK4 inhibitor while the other is the most potent dual CDK4/6 inhibitor. The later one has been approved by the TGA for phase Ia/b clinical trial for the treatment of glioblastoma and other advanced solid tumours. I have been delivering my professional roles through HDR student training and supervision and managing drug discovery and development laboratory. I have authored/coauthored 30 articles/proceedings in peer-reviewed journals and presented my research findings in international and national conferences.
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