Narcisse Mary Sither Joseph Vesudian

• Dynamic scientist with a proven track record at Sultan Abdul Aziz Shah Hospital, excelling in molecular diagnostics, and bioinformatics. Expert in next-generation sequencing (NGS) and PCR techniques, with notable success in establishing a COVID-19 surveillance laboratory, and training staff to enhance diagnostic capabilities. Passionate about advancing microbial genomics and fostering collaborative research environments. Has successfully supervised numerous research projects, resulting in high-impact publications and multiple patents.
  An experienced academic professional with several years of experience in higher education. Adept at using diverse teaching approaches to engage students of varying learning styles and abilities. As an innovative and results-driven lecturer, recognized for high productivity and efficient task execution. Skilled in curriculum development, modern instructional strategies, and academic research. Demonstrates strong communication, critical thinking, and adaptability—ensuring effective teaching methodologies, and positive student outcomes. Demonstrates strong leadership through active participation in faculty committees and curriculum development initiatives.

• Journal Publication Initiative, 2023 & 2024
• Inter Varsity International Challenge, 2023
• MTE SDG 2023 - MTE Innovation Awards, GOLD,
• Excellent Service Awards - Universiti Putra Malaysia, 2020
• "Micro World": Informative Iucel, One Health Scenic Model, Silver, 2018

• Universiti Putra Malaysia Teaching Hospital, Scientist, 09/01/21, Current, Develop and Implement COVID-19 Surveillance Lab (NGS: Oxford Nanopore & Illumina)
• Universiti Putra Malaysia, Senior Lecturer, 12/01/18, Current, Molecular Biology (Diagnostics) NGS & PCR
• Universiti Putra Malaysia, Post Doc, 07/01/17, 11/30/18, Medical Microbiology (Cell culture, PCR, RT-PCR, qPCR, ELISA)
• Universiti Putra Malaysia, Research Assistant, 05/01/15, 06/30/17, Medical Microbiology

• Vaccine Against Leptospirosis and Method of Development,2025
• Method of Diagnosing A Leptospirosis Infection Caused by A Leptospira Species In A Subject and A Cluster to Which the Leptospira Species Belongs, Multiplex Primer Assay, and Diagnostic Kit Thereof,2024
• 3D Model with Augmented Reality - UPM, 2018

1. Surendran, Yocyny & Vityashri, Parameswaran & Juhari, Nazwin & Karuppiah, Thilakavathy & Xiong, Chenglong & Sither Joseph, Narcisse. (2024). Unmasking the Global Journey: Investigation of SARS-CoV-2 Variants of Interest Across Various Regions Through Whole-Genome and Phylogenetic Analysis. Jundishapur Journal of Microbiology. 17. 10.5812/jjm-143544.
2. Selvavinayagam ST, Suvaithenamudhan S, Yong YK, Hemashree K, Rajeshkumar M, Kumaresan A, Arthydevi P, Kannan M, Gopalan N, Vignesh R, Murugesan A, Sivasankaran MP, Sankar S, Cheedarla N, Anshad AR, Govindaraj S, Zhang Y, Tan HY, Larsson M, Saravanan S, Balakrishnan P, Kulanthaivel L, Singh K, Joseph N, Velu V, Byrareddy SN, Shankar EM, Raju S. Genomic surveillance of omicron B.1.1.529 SARS-CoV-2 and its variants between December 2021 and March 2023 in Tamil Nadu, India-A state-wide prospective longitudinal study. J Med Virol. 2024 Feb;96(2):e29456. doi: 10.1002/jmv.29456. PMID: 38329187.
3. Selvavinayagam ST, Karishma SJ, Hemashree K, Yong YK, Suvaithenamudhan S, Rajeshkumar M, Aswathy B, Kalaivani V, Priyanka J, Kumaresan A, Kannan M, Gopalan N, Chandramathi S, Vignesh R, Murugesan A, Anshad AR, Ganesh B, Joseph N, Babu H, Govindaraj S, Larsson M, Kandasamy SL, Palani S, Singh K, Byrareddy SN, Velu V, Shankar EM, Raju S. Clinical characteristics and novel mutations of omicron subvariant XBB in Tamil Nadu, India - a cohort study. Lancet Reg Health Southeast Asia. 2023 Sep 4;19:100272. doi: 10.1016/j.lansea.2023.100272. PMID: 38076717; PMCID: PMC10709680.
4. Surendran, Yocyny & Nandikha, Mahalingam & Amin Nordin, Syafinaz & Dhanda, Sandeep & Ali, Mohamad & Joseph, Narcisse. (2023). Vaccine development for leptospirosis: A systematic review. Asian Pacific Journal of Tropical Medicine. 16. 533-545. 10.4103/1995-7645.391775.
5. Qamer, S., Che-Hamzah, F., Misni, N., Joseph, N. M. S., Al-Haj, N. A., & Amin-Nordin, S. (2023). Deploying a Novel Approach to Prepare Silver Nanoparticle Bellamya bengalensis Extract Conjugate Coating on Orthopedic Implant Biomaterial Discs to Prevent Potential Biofilm Formation. Antibiotics (Basel, Switzerland), 12(9), 1403. https://doi.org/10.3390/antibiotics12091403.
6. Selvavinayagam, Sivaprakasam T. and Jith, Karishma S. and Kannan, Hemashree, and Yong, Yean Kong, and Suvaithenamudhan, Suvaiyarasan, and Rajeshkumar, Manivannan, and Aswathy, Bijulal, and Kalaivani, Vasudevan, and Kalpana, Raghu, and Kumaresan, Anandhazhvar, and Jayapal, Priyanka, and Kannan, Meganathan, and Gopalan, Natarajan, and Samudi, Chandramathi, and Vignesh, Ramachandran, and Murugesan, Amudhan, and Anshad, Abdul R. and Ganesh, Balasubramanian and Joseph, Narcisse and Babu, Hemalatha and Govindaraj, Sakthivel and Larsson, Marie and Kandasamy, Shree L. and Palani, Sampath and Singh, Kamalendra and Byrareddy, Siddappa and Velu, Vijayakumar and Shankar, Esaki Muthu and Raju, Sivadoss, Novel Mutations in XBB Variants of SARS-CoV-2 Decipher High Rates of Morbidity Among COVID-19 Patients in South India. http://dx.doi.org/10.2139/ssrn.4409337
7. Zohari, Z., Barkham, T., Mohamad Maswan, N., Chen, S. L., Muthanna, A., Lee, K. W., Mohd Desa, M. N., Azmai, M. N. A., Sither Joseph, N. M., & Amin-Nordin, S. (2023). Fish-associated Streptococcus agalactiae ST283: first human cases reported from Malaysia. Journal of medical microbiology, 72(6), 10.1099/jmm.0.001729.
8. Yu, C.Y., Wong, S.Y., Liew, N.W.C., Joseph, N., Zakaria, Z., Nurulfiza, I., Soe, H.J., Kairon, R., Amin-Nordin, S., Chee, H.Y. Whole genome sequencing analysis of SARS-CoV-2 from Malaysia: From alpha to Omicron (2022) Frontiers in Medicine, 9, art. no. 1001022.
9. Selvavinayagam, S.T., Yong, Y.K., Joseph, N., Hemashree, K., Tan, H.Y., Zhang, Y.,    
Rajeshkumar, M., Kumaresan, A., Kalpana, R., Kalaivani, V., Monika, A.V.D., Suvaithenamudhan, S., Kannan, M., Murugesan, A., Narayanasamy, K., Palani, S., Larsson, M., Shankar, E.M., Raju, S. Low SARS-CoV-2 viral load among vaccinated individuals infected with Delta B.1.617.2 and Omicron BA.1.1.529 but not with Omicron BA.1.1 and BA.2 variants (2022) Frontiers in Public Health, 10, art. no. 1018399.
10. Mosquill, M., Nordin, S.A., Ali, M.R.M., Joseph, N.M.S. Sequence analysis of LipL41 and LipL21: Prospective Outer Membrane Proteins (OMPs) in early diagnosing leptospirosis (2022) MethodsX, 9, art. no. 101804.
11. Sakinah, S., Priya, S.P., Mok, P.L., Munisvaradass, R., Teh, S.W., Sun, Z., Alzahrani, B., Bakar, F.A., Chee, H.-Y., Hamat, R.A., He, G., Xiong, C., Joseph, N., Tong, J.B., Wu, X., Maniam, M., Samrot, A.V., Higuchi, A., Kumar, S.S. Corrigendum: Stem Cell Therapy in Dengue Virus-Infected BALB/C Mice Improves Hepatic Injury (Front. Cell Dev. Biol.,, 9, (637270), 10.3389/fcell.2021.637270) (2021) Frontiers in Cell and Developmental Biology, 9, art. no. 800659
12. Joseph, N., Bahtiar, N., Mahmud, F., Hamid, K.A., Raman, R., Chee, H.Y., Nordin, S.A. Comparison of Automated and Manual Viral Nucleic Acid Extraction Kits for Covid-19 Detection Using qRT-PCR (2022) Malaysian Journal of Medicine and Health Sciences, 18 (1), pp. 14-19.
13. Shafqat, CH Fahrudin, Hibatullah, Narcisse, Misni, N, Nagi , Syafinaz, Amin Nordin. (2021). Citation-Indexed Journal - Science Citation Index (JCR), Full Paper, Published, MDPI, 1-21.
14. Thilakavathy K, Narcisse. (2021). Regional Prevalence of Intermediate Leptospira spp. in Humans: A Meta-Analysis. Citation-Indexed Journal - Science Citation Index (JCR), Full Paper, Accepted, Multidisciplinary Digital Publishing Institute (MDPI), 1-15.

1. SN Masri, Masri SN, Rosni Ibrahim, Syafinaz, Amin Nordin, T.Z.M.T. JAMALUDDIN, Hamat, R. A. Awang, Rukman Rukman, A. H. Rukman, Awang Hamat Awang Hamat, Rukman Hamat, Rukman Hamat, Rukman Awang Hamat, Rukman A., Z Sekawi, Mahayidin.H., Leslie, Chee H-Y, AS JASNI, Misni, N, Ithnin. Narcisse, Niazlin MT. (2023). OUTDOOR ADVENTURE TO ENHANCE LEARNING MOTIVATION IN MEDICAL MICROBIOLOGY AMONG MASTER SCHOLAR   I-PICTL 2023,   Abstract,   Non Citation-Indexed ,   UPM,   International,   0 ,  [57 - 57],  MALAYSIA.
2. Narcisse. Molecular diagnostics workshop (2022). Dept of Medical Microbiology, Faculty of Medicine & Health Sciences UPM,MALAYSIA.
3. Yocyny, Narcisse. (2021). “T-cell Epitope Mapping of Outer Membrane Protein of Leptospira. 2nd WBDS-LA 2nd WBDS LA, Argentina.
4. Muzaffar, Thilakavathy, Syafinaz, Narcisse. (2021). Sequence Analysis of LipL41 and LipL21: Prospective Outer Membrane Proteins in Early Diagnosing Leptospirosis 2nd WBDS LA Conference, Argentina.
5. Kosno K, Suresh Kumar, Narcisse, Thilakavathy k. (2020). Computational prediction of the conserved regions, 3D structure and epitope region of Leptospira LigA protein. 1st Congress of Women in Bioinformatics and Data Science Latin America , Abstract, Non Citation-Indexed , Asociación Argentina de Bioinformática y Biología Computacional, International, 978- 987-86-6367-8 , [55 - 55], ARGENTINA.
6. Sharmilah, Narcisse. (2020). Computational predicition of the conserved regions, 3D structure and epitope region of Leptospira LigA protein 1st Latin American Congress of Women in Bioinformatics and Data Science, Abstract, Non Citation-Indexed , Latin American Congress of Women in Bioinformatics and Data Science, International, 9789878663678 , [162 - 162], ARGENTINA.

1. Human Genome Meeting, Human Genome Organization IMR, Ministry of Health, 2014.
2. The Mystical Tropical Illness: A Workshop on Strengthening Basic, Optimizing Future Research in Leptospirosis. IMR, Ministry of Health, 2023.
3. International Congress of Pathology and Laboratory Medicine, 2023.
4. Oxford Nanopore Bacterial WGS Hand-On Workshop, 2023.
5. NGS Post Analysis: Variant Interpretation & Prioritization in Medical Genetics Workshop, 2023.

• Strategic Research Fund Grant Scheme, Ministry of Science & Technology, Malaysia, Development of Subunit Vaccine Candidate Against Leptospirosis (2023-2025).
• Fundamental Research Grant Scheme, Skin microbiome Diversity, Vitamin D Variation and Sociodemographic Characters of Non-melanoma Skin Cancer Patients (2023-2026).
• Fundamental Research Grant Scheme: OmpL1 as a Diagnostic Marker for Leptospira spp. (Co-Researcher, 2021-2023).
• Pfizer, AMR Gene Detection via Digital PCR (PI, 2021-2022).
• Putra Initiative, T Cell Epitopes in Leptospira (2020-2022).
• Putra Initiative, Platelet Depletion in Dengue (2018-2020).
• Putra Initiative, Gene Expression in Gastric Stem Cells (2018-2020).