Summary
Overview
Work History
Education
Skills
Publications
Patent
Timeline
Generic
Qitong Feng

Qitong Feng

Parkville,VIC

Summary

Currently pursuing a PhD in Drug Delivery at Monash University's Faculty of Pharmacy and Pharmacology Sciences. Research focuses on developing NIR-responsive linkers based on BODIPY scaffolds for targeted drug delivery using nanoparticle systems.

Overview

11
11
years of professional experience

Work History

PhD Student

Monash University
07.2023 - Current
  • Utilizing organic synthesis to develop cleavable linkers that responsible to exogenous stimuli like Near Infrared light or radio frequency.
  • Conjugating the exogenous stimuli cleavable linker to the nanoparticles like porous silicon nanoparticles or gold nanoclusters for better controlled drug release for cancer therapy.

Research Specialist

King Abdullah University of Science and Technology
01.2019 - 12.2020
  • Use LC-MS/MS techniques to analyze plant metabolism, including carotenoids, apocarotenoids, strigolactones, abscisic acid, etc
  • Three papers regarding these metabolisms have been published

Research Assistant

Macau University of Science and Technology
07.2017 - 08.2018
  • Organized protein pull-down assay from start to finish by designing an effective synthesis scheme for biotin probing and protein identification procedures
  • Five different biotin-based probes have been synthesized, and one potential binding protein has been identified

Master student

Macau University of Science and Technology
09.2013 - 02.2017
  • Use HPLC and Semi-HPLC to isolate and purify components from a Chinese herb
  • 34 compounds have been identified and two compounds have been identified as anti-influenza viruses
  • Use Organic synthesis to synthesize 16 derivatives of Aurantiamide Acetate for the further mechanism study of their anti-influenza virus activity
  • Use Organic synthesis to synthesize 10 derivatives of Gensinoside Rb1 as standards for LC-MS analysis of rats' blood

Education

Ph.D. - Drug Delivery Disposition And Dynamics

Monash University
Parkville, VIC
12-2026

Master of Science - Pharmacology in Chinese Medecine

Macau University of Science And Technology
Macau
02-2017

Bachelor - Pharmacology in Chinese Medicine

China Pharmaceutical University
06.2013

Skills

  • Organic Synthesis: Expert in complex multi-step synthesis of chromophores and fluorophores, with proven skills in reaction optimization and mechanistic analysis Proficient in scaled-up synthesis and handling light-sensitive compounds
  • Nanoparticle Engineering: Specialized in bottom-up synthesis of gold nanoclusters and porous silicon nanoparticles, with expertise in surface functionalization and comprehensive characterization (DLS, TEM, SEM, UV-Vis)
  • Analytical Chemistry: Advanced proficiency in chromatographic analysis (LC-MS, GC-MS) for molecular identification and quantification, complemented by structural determination using FT-IR and multinuclear NMR spectroscopy
  • Computational Chemistry: Expert in quantum chemical calculations using GAUSSIAN, focusing on electronic structure analysis and modeling of organic dyes and nanomaterials

Publications

  • Zhou B, Yang Z, Feng, Q., et al. Aurantiamide acetate from baphicacanthus cusia root exhibits anti-inflammatory and anti-viral effects via inhibition of the NF-κB signaling pathway in Influenza A virus-infected cells [J]. Journal of ethnopharmacology, 2017, 199: 60-67. (Times Cited 49)
  • Zhou, B., Liang, X., Feng, Q., Li, J., Pan, X., Xie, P., ... & Yang, Z. (2019). Ergosterol peroxide suppresses influenza A virus-induced pro-inflammatory response and apoptosis by blocking RIG-I signaling. European journal of pharmacology, 860, 172543. (Times Cited 14)
  • Feng, Q., Zhu, G., Gao, W., et al. Two New Alkaloids from the Roots of Baphicacanthus cusia [J]. Chemical & pharmaceutical bulletin, 2016, 64(10): 1505. (Times Cited 16)
  • Mi, J., Jia, K. P., Balakrishna, A., Feng, Q., & Al-Babili, S. (2019). A Highly Sensitive SPE Derivatization–UHPLC–MS Approach for Quantitative Profiling of Carotenoid-Derived Dialdehydes from Vegetables. Journal of agricultural and food chemistry, 67(20), 5899-5907. (Times Cited 10)
  • Wang, J. R., Yau, L. F., Tong, T. T., Feng, Q., Bai, L. P., Ma, J., ... & Jiang, Z. H. (2015). Characterization of oxygenated metabolites of ginsenoside Rb1 in plasma and urine of rat. Journal of agricultural and food chemistry, 63 (10), 2689-2700. (Times Cited 12)
  • Ablazov, A., Mi, J., Jamil, M., Jia, K.P., Wang, J.Y ., Feng, Q. and Al-Babili, S., 2020. The Apocarotenoid Zaxinone Is a Positive Regulator of Strigolactone and Abscisic Acid Biosynthesis in Arabidopsis Roots. Frontiers in Plant Science, 11, p.578. (Times Cited 26)
  • Jia, K. P., Mi, J., Ablazov, A., Ali, S., Yang, Y ., Balakrishna, A., ... & Al-Babili, S. (2021). Iso-anchorene is an endogenous metabolite that inhibits primary root growth in Arabidopsis. Plant J, 10(10), 15271. (Times Cited 9)

Patent

  • Jing-Rong W, Jiang Z, Feng Q, et al. Method of isolating anti-viral ingredients from baphicacanthus cusia, compositions comprising them and their medical use: U.S. Patent Application US 2017/0281702. 2017-10-5.
  • Jiang Zhi-hong, Zhong Nanshan, Yang Zifeng, Wang Jing-Rong, Feng Qitong, et al. Compounds and methods for treating influenza, Australia Patent Application, AU 2020103878. 2021-01-27
  • Zifeng Yang, Beixian Zhou, Feng Q, et al. Application of peroxy-ergosterol in drug resisting influenza virus infection and preparation of peroxy-ergosterol; China Patent Application CN106432400A. 2017-02-22.
  • Zifeng Yang, Beixian Zhou, Feng Q, et al. Application of aurantiamide acetate in anti-influenza virus medicine and preparation of aurantiamide acetate; China Patent Application CN106431960A. 2017-02-22.
  • Jing-Rong W, Jiang Z, Feng Q, et al. Method of isolating anti-viral ingredients from baphicacanthus cusia, compositions comprising them and their medical use: U.S. Patent Application AU 2016100366 A4. 2016-5-12.
  • Jiang Zhi-hong, Zhong Nanshan, Yang Zifeng, Wang Jing-Rong, Feng Qitong, et al. Compounds and methods for treating influenza, U.S. Patent Application, US9345690B2. 2022-04-8.

Timeline

PhD Student

Monash University
07.2023 - Current

Research Specialist

King Abdullah University of Science and Technology
01.2019 - 12.2020

Research Assistant

Macau University of Science and Technology
07.2017 - 08.2018

Master student

Macau University of Science and Technology
09.2013 - 02.2017

Bachelor - Pharmacology in Chinese Medicine

China Pharmaceutical University

Ph.D. - Drug Delivery Disposition And Dynamics

Monash University

Master of Science - Pharmacology in Chinese Medecine

Macau University of Science And Technology
Qitong Feng