Simran Nathwani
Ahmedabad
Summary
As a dedicated professional in the biotechnology sector, I bring a practical approach combined with a companionable disposition and deep-rooted cultural values. My career is marked by a steadfast commitment to accuracy in all aspects of my work, ensuring reliability and precision essential in the biotechnological landscape. I am a firm believer in the power of clear, effective communication, and I leverage these skills to foster transparency and contribute to organizational growth. My background equips me to navigate the complexities of biotechnology, while my interpersonal skills enable me to collaborate effectively with diverse teams, driving innovation and excellence in this dynamic field.
Overview
2
2
years of professional experience
Work History
Senior Scientific Assistant
Zydus Research Centre
Ahmedabad
12.2021 - Current
- Skilled in small molecule drug discovery, with a focus on Idiopathic Pulmonary Fibrosis and Rheumatoid Arthritis projects, demonstrating a thorough understanding of both basic and advanced research workflows..
- Proficient in cell culture and cell-based assays, specializing in the management of various mammalian cell cultures under aseptic conditions.
- Currently working on whole project of Zydus wellness products including cytotoxic and skin sensitization assay studies (experiments designing, performing, data generation and report submission) including cellular ATP assay, cell proliferation, luciferase assay, transfection and transformation.
- Actively involved in the Investigational New Drug (IND) study of the ATX inhibitor ZYAT1, focusing on treatments for Idiopathic Pulmonary Fibrosis.
- Experienced in conducting a range of cell-based assays, including cell proliferation assays using MTT and other endpoints, as well as cytokine release assays with ELISA endpoints. Proficient in executing assays with standard New Chemical Entities (NCEs) to validate and reproduce measurement parameters.
- Skilled in preparing cell lysates, conducting protein estimation, and proficient in SDS-PAGE and Western blot techniques.
- Proficient in standard molecular biology techniques, including plasmid isolation from bacterial cultures, DNA/RNA quantification, DNA agarose gel electrophoresis, restriction digestion, PCR, and gel documentation.
- Adept at literature review and experimental plan design for diseases like Oncology, Arthritis, Pain, and Inflammation, with a focus on current and emerging targets. Extensively informed on various cell-based and cell-free assays and techniques, and their application in drug discovery research.
- Proficient in maintaining accurate and up-to-date data records, both in traditional lab notebooks and Electronic Lab Notebooks (ELN), ensuring compliance with standard documentation practices.
- Skilled in a variety of computational tools and software, including MS Office, GraphPad Prism, and specialized instrumental software, enhancing data analysis and presentation capabilities.
Education
Master of Science - Biotechnology
Sardar Patel University
Anand, India07-2021
Bachelor of Science - Biotechnology
Saurashtra University
Amreli, India04-2019
Skills
- Basic cell culture, Media preparation, Culture Maintenance
- Molecular Biology: Plasmid Preparation, Transient transfection, Transformation, DNA/RNA Isolation, RT-PCR, SDS PAGE
- Binding Assay: Fluorescence Polarization and SPR(Surface Plasmon Resonance)
- Familiar with ELISA, Luciferase assay system, Western Blot and Protein estimation
- Cytotoxicity Assay: MTT and ATP-Glo assay
- Microsoft Office and Graphpad Prism
- Interpersonal and Written Communication
Publications
- Panigrahi J, Rathod S, Nathwani S, Patel S, Patel IC (2020). COVID-19- A biological terror. The outbreak of COVID-19 disease and its impact on Global Health. Shriyanshi Prakashan, Agra. (ISBN: 978-93-81247-44-0).
- Panigrahi J, Ram N, Rathod S, Nathwani S, Patel S (2020). Food security- The current scenario amidst COVID-19. https://planetagriculture.in/food-security-the-current-scenario-amidst-covid-19/
- Panigrahi J, Nathwani S, Rathod S (2021). Food safety: Another Soldiery to Save life. Asian Journal of Research in Pharmaceutical Sciences. 11(1):81-85, doi: 10.5958/22315659.2021.00013.8
- Rupapara, R., Patel, S., Vasani, M., Nathwani, S. A., Panigrahi, M., & Panigrahi, J. (2022). Composite effects of gibberellic acid and kinetin on the postharvest-life of Solanum melongena L. Egyptian Journal of Agricultural Research, 101(1), 35-44.
- Vaishnani, B., Nathwani, S. A., Baraiya, T., & Panigrahi, J. (2022). Physiological, biochemical, and enzymatic implications of “salt and lead” tolerance in Cicer arietinum under hydroponic culture condition. Egyptian Journal of Agricultural Research, 100(4), 483-498.
- Nathwani, S., Vaishnani, B., Baraiya, T., & Panigrahi, J. (2022). Chromium and salt induced perturbation in growth, physiobiochemical and enzymatic attributes in Vigna radiata (L.) WILCZEK. Analele Universitatii din Oradea, Fascicula Biologie, 29(2).
Languages
Gujarati
First Language
English
Advanced (C1)
C1
Hindi
Advanced (C1)
C1
References
References available upon request.
Timeline
Senior Scientific Assistant
Zydus Research Centre
12.2021 - Current
Master of Science - Biotechnology
Sardar Patel University
Bachelor of Science - Biotechnology
Saurashtra University
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